Description

TB-500, also known as Thymosin Beta-4, is a synthetic peptide derived from a naturally occurring protein in the human body. It plays a role in cell migration, tissue repair, and regeneration.

TB-500 is being researched for its potential in various therapeutic areas. In terms of tissue repair and regeneration, studies are exploring its ability to accelerate wound healing and enhance muscle recovery. (1) TB-500 has been shown to promote cell migration and angiogenesis, both of which are essential for effective tissue repair. Additionally, research is examining its role in reducing inflammation and modulating immune responses, which could benefit those with chronic inflammatory conditions. (2)

In the realm of sports medicine, TB-500 is being studied for its potential to improve athletic performance by reducing recovery time from injuries. However, its use in sports remains controversial and is not approved by major sports organizations. (3)  Furthermore, researchers are evaluating its therapeutic potential for chronic diseases involving tissue damage or degeneration, such as cardiovascular and neurodegenerative disorders. (4)

(1) Goldstein, A. L., & Kleinman, H. K. (2015). Advances in the basic and clinical applications of thymosin β4. Expert Opinion on Biological Therapy, 15(sup1), 139–145. https://doi.org/10.1517/14712598.2015.1011617

(2) Sosne, G., Qiu, P., & Kurpakus-Wheater, M. (2007). Thymosin beta 4: A novel corneal wound healing and anti-inflammatory agent. Clinical ophthalmology, 1(3), 201-207.

(3) Thevis, M., Thomas, A., & Schänzer, W. (2014). Detecting peptidic drugs, drug candidates and analogs in sports doping: current status and future directions. Expert Review of Proteomics, 11(6), 663–673. https://doi.org/10.1586/14789450.2014.965159

(4) Kim, J., & Jung, Y. (2015). Potential role of thymosin Beta 4 in liver fibrosis. International journal of molecular sciences, 16(5), 10624-10635.

Additional information