Description

Kisspeptin-10 is a synthetic peptide derived from the naturally occurring kisspeptin, a hormone critical for regulating reproductive hormone secretion. It is composed of ten amino acids and plays a role in the endocrine system by stimulating the release of hormones involved in reproductive functions. (1) Kisspeptin-10 is particularly notable for its influence on testosterone levels and its potential effects on sex drive and motivation. (2) Research also indicates that it may help mitigate some age-related hormonal changes, thereby offering possible benefits in addressing reproductive health and age-associated hormonal decline.

(1)Jayasena, C. N., Nijher, G. M., Comninos, A. N., Abbara, A., Januszewki, A., Vaal, M. L., Sriskandarajah, L., Murphy, K. G., Farzad, Z., Ghatei, M. A., Bloom, S. R., & Dhillo, W. S. (2011). The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans. The Journal of clinical endocrinology and metabolism, 96(12), E1963–E1972. https://doi.org/10.1210/jc.2011-1408

(2) Jayasena, C. N., Abbara, A., Narayanaswamy, S., Comninos, A. N., Ratnasabapathy, R., Bassett, P., Mogford, J. T., Malik, Z., Calley, J., Ghatei, M. A., Bloom, S. R., & Dhillo, W. S. (2015). Direct comparison of the effects of intravenous kisspeptin-10, kisspeptin-54 and GnRH on gonadotrophin secretion in healthy men. Human reproduction (Oxford, England), 30(8), 1934–1941. https://doi.org/10.1093/humrep/dev143

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